SINCE World war 2, medical science has progressed with a stage where competitive medications are available to treat exactly the same ailment in several people. It’s not almost brands (the trade issue) but generic drugs (the scientific issue). In this report, we shall look at the various factors that decide your selection of a specific drug.
Safety: The next sub-criteria should be considered beneath the criterion of safety:
* Acute therapeutic index: When the patient’s condition is acute, how effective is really a particular drug even when it’s certain side-effects providing the acuteness of the condition is lowered? Example: narcotic pain-killers are incredible in healing pain but come with the opportunity side-effect of addiction.
* Long-term safety: medicationdirectory.com may be safe in short-term treatment, so how safe it can be in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but sometimes have undesirable effects in case there is prolonged use.
* Drug-drug interaction risk: Medicine is chemicals, and several chemicals react to create a different chemical, that have an effect that could harm the person or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.
Drug-drug interaction risk is of two types:
· Pharmacokinetic: In this type of drug-drug interaction, two drugs, separate from the other, have certain effects on a single or maybe more body processes (e.g., metabolism) that affects the performance of the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) depends upon for the metabolism. This leads to a boost in the side-effects of Lexapro.
· Pharmacodynamic: Here, several drugs actually create the same effect on exactly the same organ, thus helping the total, added effect. Example: Lexapro has certain side-effects including drowsiness and fatigue. Darvocet-N also acts similarly for the brain. Thus, the side-effects of the two prescription medication is more intense.
Tolerability: A medication may be effective however, not tolerable by all patients. Example: Allergies to certain drugs in some people. Short-term and long-term tolerability need to be taken into account. Efficacy: A medication is just not equally good at all patients. For instance, some patients with depression or anxiety disorders experience rest from escitalopram, but there are many that do not, who therefore need to be prescribed a different anti-depressant. The speed of beginning of therapeutic action is a crucial the answer to be regarded too.
Cost: Cost does not mean the price of acquiring a specific medicine alone. It must also cover the price of management of a complication that could arise while using a different drug. Example: In the individual who insists on taking alcohol and yet must be treated for depression is generally administered an SSRI drug because these drugs don’t potentiate the consequences of alcohol, whereas another band of anti-depressants (including tricyclics) might cause a fresh overuse injury in such patients, which may need a different and expensive treatment. Therefore, it’s safer to prescribe the more costly escitalopram instead of a cheaper tricyclic such patients.
Simplicity of treatment: The best mode of administration is preferred. If you have an alternative between a shot and oral administration, aforementioned is preferred if the efficacy of the two modes is the identical. Or, local application is preferred to the oral route where possible; e.g., antibiotic management of eye infections. Dosage and frequency of administration too are key point to make a decision simplicity of treatment.
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